Binod Dhakal Selected Research

Immunoglobulin Subunits

12/2017

Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis.

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Binod Dhakal Research Topics

Disease

40	Multiple Myeloma 12/2022 - 01/2016
11	Neoplasms (Cancer) 01/2022 - 12/2017
6	Thrombocytopenia (Thrombopenia) 10/2020 - 01/2017
6	Amyloidosis 06/2020 - 12/2014
5	Immunoglobulin Light-chain Amyloidosis 06/2020 - 12/2014
4	Residual Neoplasm 09/2022 - 01/2016
4	Infections 01/2022 - 10/2018
4	Plasma Cell Leukemia 07/2021 - 12/2020
4	Thrombosis (Thrombus) 01/2020 - 01/2017
3	Fever (Fevers) 10/2021 - 01/2004
2	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 05/2018
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020 - 10/2018
2	Primary Myelofibrosis (Myelosclerosis) 01/2020 - 01/2016
2	Lymphoma (Lymphomas) 10/2018 - 10/2016
2	Hemorrhage 05/2018 - 01/2017
1	POEMS Syndrome (Syndrome, POEMS) 12/2022
1	Bites and Stings (Sting) 11/2022
1	Diarrhea 10/2021
1	Exanthema (Rash) 10/2021
1	Sarcopenia 01/2021
1	Renal Insufficiency (Renal Failure) 01/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021
1	Frailty 11/2020
1	Fatigue 10/2020
1	Bronchiolitis Obliterans Syndrome 10/2020
1	Leukopenia 10/2020
1	Disease Progression 01/2020
1	Splenomegaly 01/2020
1	Paraproteinemias (Monoclonal Gammopathy) 01/2020
1	Neutropenia 01/2019
1	Mucositis 01/2019
1	Circulating Neoplastic Cells 11/2018
1	Hypotension (Low Blood Pressure) 05/2018

Drug/Important Bio-Agent (IBA)

4	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 01/2019
4	Proteasome InhibitorsIBA 01/2021 - 01/2016
4	Melphalan (Alkeran)FDA LinkGeneric 12/2020 - 01/2018
4	Biomarkers (Surrogate Marker)IBA 11/2020 - 11/2018
4	Heparin (Liquaemin)FDA LinkGeneric 01/2020 - 01/2017
3	Lenalidomide (CC 5013)FDA Link 01/2022 - 01/2019
3	Chimeric Antigen ReceptorsIBA 01/2022 - 01/2021
3	Propranolol (Inderal)FDA LinkGeneric 01/2022 - 05/2018
3	Monoclonal AntibodiesIBA 01/2022 - 01/2020
3	Bortezomib (Velcade)FDA Link 01/2022 - 01/2019
3	plerixafor FDA Link 12/2019 - 12/2014
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 01/2021
2	carfilzomibIBA 01/2022 - 01/2021
2	daratumumabIBA 01/2022 - 01/2021
2	pembrolizumabIBA 10/2021 - 01/2019
2	Etoposide (VP 16)FDA LinkGeneric 01/2021 - 10/2016
2	Immunoglobulins (Immunoglobulin)IBA 01/2021 - 01/2015
2	ixazomibIBA 10/2020 - 01/2019
2	Doxycycline (Periostat)FDA LinkGeneric 06/2020 - 12/2017
2	Intravenous Immunoglobulins (IVIG)FDA Link 01/2020 - 01/2017
2	ruxolitinibIBA 01/2020 - 01/2016
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2019 - 12/2014
2	Propylene Glycol (1,2 Propanediol)FDA LinkGeneric 01/2018 - 01/2018
2	AntibodiesIBA 10/2017 - 01/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 12/2014 - 01/2004
1	mRNA VaccinesIBA 11/2022
1	Circulating Tumor DNAIBA 01/2022
1	ParaffinIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	B-Cell Maturation AntigenIBA 01/2022
1	Budesonide (Pulmicort)FDA LinkGeneric 10/2021
1	Cholinergic Agents (Cholinergics)IBA 01/2021
1	Cholinergic ReceptorsIBA 01/2021
1	CXC ChemokinesIBA 01/2021
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2021
1	Bispecific AntibodiesIBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021
1	LigandsIBA 01/2021
1	Thalidomide (Thalomid)FDA Link 01/2021
1	Prostaglandins FIBA 12/2020
1	Indicators and Reagents (Reagents)IBA 11/2020
1	fludarabineIBA 01/2020
1	Busulfan (Busulfex)FDA Link 01/2020
1	Immunomodulating AgentsIBA 01/2020
1	Factor X (Stuart Factor)IBA 03/2019
1	Warfarin (Coumadin)FDA LinkGeneric 03/2019
1	Genetic Markers (Genetic Marker)IBA 01/2019
1	Bendamustine Hydrochloride FDA Link 01/2019
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 11/2018
1	Antineoplastic Agents (Antineoplastics)IBA 05/2018

Therapy/Procedure

25	Cell Transplantation 12/2022 - 01/2016
24	Therapeutics 09/2022 - 09/2011
7	Drug Therapy (Chemotherapy) 01/2022 - 09/2011
6	Transplantation 01/2022 - 01/2020
5	Immunotherapy 01/2022 - 01/2016
3	Stem Cell Transplantation 01/2022 - 10/2021
3	Autologous Transplantation 01/2019 - 01/2016
3	Length of Stay 10/2018 - 08/2013
2	Total Parenteral Nutrition 01/2019 - 10/2018
1	Withholding Treatment 01/2022
1	Salvage Therapy 01/2021
1	Patient Readmission 12/2020
1	Plasma Exchange 08/2020
1	Kidney Transplantation 01/2020
1	Hematopoietic Stem Cell Mobilization 12/2019